Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a delightful dish that brings together rich flavors and creamy textures. This recipe is perfect for family dinners, gatherings, or even a cozy night in. With its bold Cajun seasoning and decadent cheese sauce, it stands out as a comforting meal that everyone will love.

Jump to:
- Why You’ll Love This Recipe
- Tools and Preparation
- Essential Tools and Equipment
- Importance of Each Tool
- Ingredients
- For the Chicken
- For the Pasta
- For the Sauce
- For Garnish
- How to Make Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Step 1: Boil the Pasta
- Step 2: Season the Chicken
- Step 3: Sear the Chicken
- Step 4: Prepare the Sauce Base
- Step 5: Make It Creamy
- Step 6: Add Cheeses
- Step 7: Season Your Sauce
- Step 8: Combine Pasta
- Step 9: Serve Hot
- How to Serve Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- With a Side Salad
- Topped with Additional Cheese
- Accompanied by Garlic Bread
- Garnished with Fresh Herbs
- Served in Individual Bowls
- How to Perfect Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Best Side Dishes for Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Common Mistakes to Avoid
- Storage & Reheating Instructions
- Refrigerator Storage
- Freezing Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Reheating Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Frequently Asked Questions
- Can I use other types of pasta?
- How spicy is Cajun seasoning?
- Can I make this dish dairy-free?
- Is this recipe suitable for meal prep?
- What sides pair well with Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce?
- Final Thoughts
- 📖 Recipe Card
Why You’ll Love This Recipe
- Quick and Easy: This dish can be prepared in just 35 minutes, making it perfect for busy weeknights.
- Flavor Explosion: The combination of Cajun seasoning, garlic, and creamy cheeses creates an irresistible taste that will leave your guests asking for more.
- Versatile Dish: Serve it on its own or pair it with a side salad for a complete meal; it’s suitable for various occasions.
- Crowd-Pleaser: With its creamy texture and savory chicken, this recipe is sure to please both kids and adults alike.
- Customizable: Adjust the level of spice with the Cajun seasoning and crushed red pepper flakes to suit your taste.
Tools and Preparation
Before diving into this flavorful dish, make sure you have the right tools on hand. Having everything ready will streamline your cooking process.
Essential Tools and Equipment
- Large pot
- Skillet
- Cooking spoon
- Measuring cups and spoons
- Knife and cutting board
Importance of Each Tool
- Large pot: Essential for boiling pasta evenly without overcrowding.
- Skillet: Perfect for searing chicken and creating the delicious sauce.
- Cooking spoon: Helps in mixing ingredients thoroughly to achieve a smooth sauce.
- Knife and cutting board: Crucial for preparing ingredients quickly and safely.

Ingredients
For the Chicken
- 1 lbs boneless, skinless chicken breasts, cut into bite-sized pieces
- 2 tbsp olive oil
- 1 tsp Cajun seasoning, adjust to taste
- Salt and black pepper, to taste
For the Pasta
- 12 oz rotini pasta
For the Sauce
- 3 tbsp unsalted butter, divided
- 4 cloves garlic, minced
- 1 cup heavy cream
- 1 cup shredded mozzarella cheese
- 1/2 cup freshly grated Parmesan cheese
- 1 tsp Italian seasoning
- Crushed red pepper flakes, to taste
For Garnish
- Fresh chopped parsley
How to Make Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Step 1: Boil the Pasta
Boil a large pot of salted water. Add the rotini and cook until al dente, about 9-10 minutes. Reserve 1 cup of the pasta water, then drain and set aside.
Step 2: Season the Chicken
Season the chicken pieces with Cajun seasoning, salt, and pepper. Toss until evenly coated.
Step 3: Sear the Chicken
Heat olive oil and 1 tablespoon of butter in a large skillet over medium-high heat. Add the chicken and sear for 7-8 minutes until golden brown and cooked through, stirring occasionally. In the last minute, stir in half of the minced garlic to infuse flavor. Remove chicken from skillet and set aside.
Step 4: Prepare the Sauce Base
Lower heat to medium. Add the remaining 2 tablespoons of butter to the same skillet, followed by the rest of the garlic. Sauté for about 30 seconds until fragrant.
Step 5: Make It Creamy
Pour in the heavy cream while stirring as it heats. Let it simmer for about 2-3 minutes until slightly thickened.
Step 6: Add Cheeses
Stir in mozzarella and Parmesan cheeses until melted into a thick, velvety sauce.
Step 7: Season Your Sauce
Season the sauce with Italian seasoning, crushed red pepper flakes (if using), plus salt and pepper to taste.
Step 8: Combine Pasta
Add cooked rotini to the skillet and toss until all spirals are coated with that creamy Cajun cheese sauce. If needed, add a splash of reserved pasta water to loosen up the sauce.
Step 9: Serve Hot
Serve your cheesy rotini hot with Cajun chicken spooned on top or folded in. Garnish with fresh parsley and extra cheese if desired. Enjoy!
How to Serve Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a delightful and filling dish that can be served in various ways. Whether you want to impress guests or enjoy a cozy family meal, here are some serving suggestions to elevate your dining experience.
With a Side Salad
- A fresh side salad of mixed greens, cherry tomatoes, and cucumbers adds brightness and crunch, balancing the richness of the rotini.
Topped with Additional Cheese
- Sprinkling extra mozzarella or Parmesan cheese on top just before serving creates an indulgent finish that appeals to cheese lovers.
Accompanied by Garlic Bread
- Serve alongside warm garlic bread for a hearty complement. The buttery, garlicky flavor pairs wonderfully with the creamy sauce.
Garnished with Fresh Herbs
- Fresh chopped parsley or basil not only enhances the visual appeal but also adds a pop of freshness that cuts through the richness of the dish.
Served in Individual Bowls
- Presenting the rotini in individual bowls makes for an elegant serving style, perfect for dinner parties or special occasions.
How to Perfect Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Perfecting this dish comes down to a few key techniques. Here are some tips to ensure your Cajun Chicken Rotini turns out amazing every time.
Season Generously: Don’t skimp on the Cajun seasoning. It’s essential for achieving that signature flavor profile, so taste as you go!
Use High-Quality Cheese: Opt for fresh mozzarella and Parmesan instead of pre-shredded cheese. Fresh cheese melts better and enhances the overall creaminess.
Adjust Cream Consistency: If the sauce is too thick, gradually add reserved pasta water until you reach your desired consistency for coating the rotini perfectly.
Infuse Flavor Early: Searing the chicken with garlic infuses deep flavors into both the meat and sauce. Ensure you toss in garlic at the right moment for maximum impact.
Best Side Dishes for Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Pairing side dishes with your Cajun Chicken Rotini can enhance your meal significantly. Here are some fantastic options to consider:
Garlic Roasted Vegetables
A mix of seasonal vegetables roasted until tender and caramelized offers a delicious contrast to the creamy pasta.Coleslaw
A crunchy coleslaw provides a refreshing contrast that complements the rich flavors of the rotini beautifully.Steamed Broccoli
Lightly steamed broccoli adds color and nutrients while its slight bitterness balances out the creaminess of the dish.Caesar Salad
Classic Caesar salad with crunchy croutons and tangy dressing adds texture and pairs wonderfully with cheesy pasta dishes.Corn on the Cob
Grilled or boiled corn on the cob provides sweetness that contrasts nicely with spicy flavors in the rotini.Baked Sweet Potatoes
Soft, sweet baked potatoes offer a comforting side that works well alongside rich pasta dishes like this one.Stuffed Bell Peppers
Colorful bell peppers stuffed with quinoa or rice provide a healthy option that complements this creamy dish nicely.Creamy Mashed Potatoes
For those who love comfort food, creamy mashed potatoes can absorb all those delicious sauces from your plate!
Common Mistakes to Avoid
Cooking Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce can be a delightful experience, but certain mistakes can hinder your dish’s success.
- Bold seasoning choices: Not adjusting the Cajun seasoning to your taste can result in an overpowering or bland flavor. Start with less and add more as needed.
- Overcooking pasta: Cooking rotini too long can lead to mushy pasta. Always check for al dente texture, which should take about 9-10 minutes.
- Neglecting garlic timing: Adding garlic too early can cause it to burn and taste bitter. Sauté it for just 30 seconds before adding liquids for the best flavor.
- Ignoring cheese meltability: Adding cold cheese to a hot sauce can prevent it from melting smoothly. Always ensure your sauce is hot enough before stirring in the cheeses.
- Skipping reserved pasta water: Forgetting to save some pasta water may leave your sauce too thick. Use it to loosen the sauce and get that creamy texture.
- Not garnishing: Serving without a fresh herb garnish can make your dish look less appealing. A sprinkle of parsley adds color and freshness.

Storage & Reheating Instructions
Refrigerator Storage
- Store leftovers in an airtight container.
- Keep in the refrigerator for up to 3 days for optimal freshness.
Freezing Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- This dish can be frozen for up to 2 months.
- Use freezer-safe containers or resealable bags to prevent freezer burn.
Reheating Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Oven: Preheat your oven to 350°F (175°C). Place the rotini in an oven-safe dish, cover with foil, and heat for about 20-25 minutes.
- Microwave: Heat in a microwave-safe bowl on medium power for 2-3 minutes, stirring halfway through until heated evenly.
- Stovetop: Add a splash of water or reserved pasta water in a skillet over medium heat. Stir frequently until warmed through.
Frequently Asked Questions
Here are some common questions about making Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce.
Can I use other types of pasta?
You can certainly substitute other pasta shapes like penne or fusilli if you prefer. Just adjust cooking times as needed.
How spicy is Cajun seasoning?
Cajun seasoning varies by brand; start with a small amount and increase based on your spice tolerance.
Can I make this dish dairy-free?
Yes, you can use dairy-free cream alternatives and omit cheese or use plant-based cheese options to suit dietary preferences.
Is this recipe suitable for meal prep?
Absolutely! This dish stores well and makes excellent leftovers, perfect for meal prepping throughout the week.
What sides pair well with Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce?
Consider serving it with a light salad or garlic bread for a complete meal experience.
Final Thoughts
This Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is not only delicious but also versatile. Feel free to customize it by adding vegetables like bell peppers or spinach, making it perfect for any occasion. Try this recipe today and enjoy its creamy goodness!
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Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Total Time: 35 minutes
- Yield: Serves 4
Description
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a mouthwatering dish that combines tender chicken, spiraled pasta, and a rich, creamy sauce infused with Cajun spices. Perfect for family dinners or casual gatherings, this recipe is not just a meal but an experience that tantalizes your taste buds. The bold flavors of Cajun seasoning meld beautifully with mozzarella and garlic butter, creating a comforting dish that’s both satisfying and simple to prepare.
Ingredients
- 1 lb boneless, skinless chicken breasts
- 12 oz rotini pasta
- 3 tbsp unsalted butter
- 1 cup heavy cream
- 1 cup shredded mozzarella cheese
- 4 cloves garlic
- Cajun seasoning to taste
- 2 tbsp olive oil
- Salt and black pepper to taste
Instructions
- Boil salted water in a large pot; cook rotini until al dente (9-10 minutes). Drain, reserving 1 cup of pasta water.
- Season chicken pieces with Cajun seasoning, salt, and pepper.
- Heat olive oil and 1 tbsp butter in a skillet over medium-high heat; sear the chicken for 7-8 minutes until golden brown. Add half the minced garlic in the last minute.
- Lower heat; add remaining butter and garlic to the skillet, sauté for 30 seconds.
- Pour in heavy cream; simmer for 2-3 minutes until slightly thickened.
- Stir in mozzarella and Parmesan cheese until melted.
- Combine cooked rotini with sauce; adjust consistency using reserved pasta water as needed.
- Prep Time: 10 minutes
- Cook Time: 25 minutes
- Category: Main
- Method: Searing/Boiling
- Cuisine: Cajun
Nutrition
- Serving Size: 1 bowl (approximately 300g)
- Calories: 620
- Sugar: 3g
- Sodium: 600mg
- Fat: 32g
- Saturated Fat: 17g
- Unsaturated Fat: 14g
- Trans Fat: 0g
- Carbohydrates: 54g
- Fiber: 3g
- Protein: 32g
- Cholesterol: 110mg





