Mac and Cheese Meatloaf Casserole is a comfort food dream come true! This dish combines a savory ground beef meatloaf with creamy macaroni and cheese on top, making it perfect for family dinners or casual gatherings. The blend of flavors and textures creates a satisfying meal that everyone will love. Whether you’re serving it for a weeknight dinner or a special occasion, this casserole will surely impress.

Jump to:
- Why You’ll Love This Recipe
- Tools and Preparation
- Essential Tools and Equipment
- Importance of Each Tool
- Ingredients
- For the Meatloaf Base
- For the Mac and Cheese Topping
- How to Make Mac and Cheese Meatloaf Casserole
- Step 1: Preheat the Oven
- Step 2: Prepare the Meatloaf Mixture
- Step 3: Bake the Meatloaf
- Step 4: Cook Macaroni Noodles
- Step 5: Make Cheese Sauce
- Step 6: Combine & Final Bake
- Step 7: Serve
- How to Serve Mac and Cheese Meatloaf Casserole
- Garnish with Fresh Herbs
- Pair with a Salad
- Serve with Bread
- Add a Sauce
- How to Perfect Mac and Cheese Meatloaf Casserole
- Best Side Dishes for Mac and Cheese Meatloaf Casserole
- Common Mistakes to Avoid
- Storage & Reheating Instructions
- Refrigerator Storage
- Freezing Mac and Cheese Meatloaf Casserole
- Reheating Mac and Cheese Meatloaf Casserole
- Frequently Asked Questions
- What is Mac and Cheese Meatloaf Casserole?
- How do I customize my Mac and Cheese Meatloaf Casserole?
- Can I use other meats instead of beef?
- How long does it take to cook Mac and Cheese Meatloaf Casserole?
- Final Thoughts
- 📖 Recipe Card
Why You’ll Love This Recipe
- Easy to Prepare: With straightforward steps, you can whip up this delicious casserole in no time.
- Flavorful Combination: The rich taste of meatloaf paired with cheesy macaroni creates a unique flavor profile that’s hard to resist.
- Great for Leftovers: This casserole reheats beautifully, making it an excellent choice for meal prep or leftovers.
- Versatile Dish: You can easily modify the recipe to include your favorite cheeses or add veggies for an extra nutritional boost.
- Crowd-Pleaser: Perfect for feeding hungry families or guests, this dish is sure to satisfy everyone at the table.
Tools and Preparation
Before diving into the cooking process, gather your essential tools. Having everything ready makes the preparation smoother and more enjoyable.
Essential Tools and Equipment
- Mixing bowls
- Baking dish (9 x 13 inches)
- Ziploc bags
- Rolling pin
- Whisk
Importance of Each Tool
- Mixing bowls: Essential for combining ingredients evenly without mess.
- Baking dish: Provides the right space to bake your casserole evenly; 9 x 13 inches fits this recipe perfectly.
- Ziploc bags: Great for crushing crackers efficiently without creating crumbs everywhere.

Ingredients
For the Meatloaf Base
- 1 cup ketchup
- 1 cup Sweet Baby Ray’s Hickory & Brown Sugar barbecue sauce
- 2 lbs lean ground beef
- 30 Ritz Crackers
- 2 oz Lipton onion soup mix
- 2 eggs
For the Mac and Cheese Topping
- 3 cups macaroni noodles
- 2 cups milk
- 10.5 oz condensed cheddar cheese soup
- 1 teaspoon salt
- 1 teaspoon pepper
- 1 tablespoon garlic powder
- 1 tablespoon onion powder
- 4 cups shredded mozzarella and cheddar cheese blend
How to Make Mac and Cheese Meatloaf Casserole
Step 1: Preheat the Oven
Preheat your oven to 350°F (175°C).
Step 2: Prepare the Meatloaf Mixture
- In a medium mixing bowl, combine the ketchup and barbecue sauce. Stir until well combined and set aside.
- In a large mixing bowl, place the ground beef.
- Put the Ritz crackers in a large Ziploc bag and crush them using a rolling pin until they are fine crumbs.
- Add the crushed cracker crumbs to the bowl with the ground beef.
- Mix in the onion soup mix, eggs, and half of the ketchup-barbecue mixture into the meat mixture.
- Use your hands to thoroughly combine all ingredients until well mixed.
Step 3: Bake the Meatloaf
- Transfer the meatloaf mixture into a greased baking dish (9 x 13 inches), pressing it out evenly.
- Spread the remaining ketchup-barbecue sauce mixture on top of the meatloaf.
- Bake in preheated oven for 30 minutes.
Step 4: Cook Macaroni Noodles
While the meatloaf is baking:
1. Cook macaroni noodles according to package directions; drain well.
Step 5: Make Cheese Sauce
- In a large mixing bowl, pour in the milk and add the cheddar cheese soup. Whisk until smooth with no lumps remaining.
- Stir in salt, pepper, garlic powder, and onion powder until well combined.
- Add cooked macaroni noodles into this mixture, ensuring they are fully coated with sauce.
- Mix in 2 cups of shredded cheese until evenly distributed.
Step 6: Combine & Final Bake
- After baking for 30 minutes, remove meatloaf from oven.
- Pour macaroni mixture over the meatloaf evenly.
- Sprinkle remaining shredded cheese on top of macaroni layer.
- Return dish to oven; bake for another 17-20 minutes until cheese is melted and slightly browned.
Step 7: Serve
Remove from oven and let sit for a few minutes before slicing into portions. Serve warm and enjoy!
This Mac and Cheese Meatloaf Casserole is not just filling but also delightful, making it an excellent addition to your dinner rotation!
How to Serve Mac and Cheese Meatloaf Casserole
Serving Mac and Cheese Meatloaf Casserole can elevate your dinner experience. This hearty dish pairs well with various sides and garnishes, making it suitable for family meals or gatherings. Here are some creative serving suggestions to enhance your meal.
Garnish with Fresh Herbs
- Chopped Parsley: Sprinkle fresh parsley over the casserole for a pop of color and freshness.
- Chives: Add chopped chives for a mild onion flavor that complements the cheese.
Pair with a Salad
- Caesar Salad: A classic Caesar salad provides crunch and a tangy contrast to the richness of the casserole.
- Garden Salad: A simple garden salad with mixed greens and vinaigrette balances the dish’s heaviness.
Serve with Bread
- Garlic Bread: Warm, buttery garlic bread is perfect for soaking up any extra sauce on your plate.
- Dinner Rolls: Soft dinner rolls make for a delightful addition to your meal, perfect for sopping up flavors.
Add a Sauce
- BBQ Sauce: Drizzle more barbecue sauce over individual servings for an extra layer of flavor.
- Hot Sauce: For those who enjoy heat, a splash of hot sauce can enhance the dish’s taste.
How to Perfect Mac and Cheese Meatloaf Casserole
Perfecting your Mac and Cheese Meatloaf Casserole takes practice. However, these tips will help you achieve the best results every time you make this delicious dish.
- Use Lean Meat: Opting for lean ground beef reduces excess fat while maintaining flavor.
- Cook Noodles Al Dente: Cook macaroni noodles just until slightly firm; they will absorb some moisture while baking.
- Layer Cheese Generously: Don’t skimp on cheese; using plenty ensures a creamy texture throughout the casserole.
- Let it Rest Before Slicing: Allowing the casserole to sit for a few minutes after baking helps it set, making slicing easier.
Best Side Dishes for Mac and Cheese Meatloaf Casserole
Complementing your Mac and Cheese Meatloaf Casserole with side dishes enhances its appeal. Here are some excellent options that pair well with this comforting meal.
- Steamed Broccoli: Lightly steamed broccoli adds color and nutrients, balancing the richness of the casserole.
- Baked Sweet Potatoes: Sweet potatoes provide a sweet contrast and can be easily prepared alongside the main dish.
- Coleslaw: A crunchy coleslaw brings freshness and acidity, cutting through the creamy flavors of the casserole.
- Roasted Carrots: Sweet roasted carrots add a natural sweetness that pairs beautifully with savory meatloaf.
- Corn on the Cob: Juicy corn on the cob is fun to eat and adds texture to your meal.
- Green Beans Almondine: Crisp-tender green beans sautéed with almonds offer elegance and crunch as a side.
Common Mistakes to Avoid
When making Mac and Cheese Meatloaf Casserole, avoiding common pitfalls can lead to better results. Here are some mistakes to watch out for:
- Skipping the Mixing Step: Not fully combining the meatloaf mixture can lead to uneven texture. Make sure to mix all ingredients thoroughly for a uniform result.
- Using Too Much Liquid: Adding excessive milk or soup can make your casserole watery. Stick to the recommended measurements for the best consistency.
- Not Preheating: Baking in a cold oven can result in uneven cooking. Always preheat your oven to ensure proper baking.
- Overcooking the Pasta: Cooking macaroni noodles too long before assembling can make them mushy. Follow package instructions and keep them al dente for a better texture.
- Neglecting Seasoning: Underseasoning can dull flavors. Taste your mixtures and add more seasoning if necessary for a well-balanced dish.

Storage & Reheating Instructions
Refrigerator Storage
- Store in an airtight container.
- Keep in the refrigerator for up to 3-4 days.
Freezing Mac and Cheese Meatloaf Casserole
- Allow the casserole to cool completely before freezing.
- Wrap tightly in plastic wrap and then aluminum foil, or use a freezer-safe container.
- Can be frozen for up to 3 months.
Reheating Mac and Cheese Meatloaf Casserole
- Oven: Preheat to 350F, cover with foil, and heat for about 20-25 minutes until warmed through.
- Microwave: Place individual portions in a microwave-safe dish, cover, and heat on high for 2-3 minutes, checking halfway.
- Stovetop: Heat on medium-low in a skillet with a splash of milk to maintain moisture, stirring occasionally until heated through.
Frequently Asked Questions
Here are some frequently asked questions about Mac and Cheese Meatloaf Casserole that may help you while preparing this dish.
What is Mac and Cheese Meatloaf Casserole?
Mac and Cheese Meatloaf Casserole is a comforting dish featuring a ground beef meatloaf base topped with creamy macaroni and cheese.
How do I customize my Mac and Cheese Meatloaf Casserole?
You can add vegetables like spinach or bell peppers, or substitute different cheeses based on your preference.
Can I use other meats instead of beef?
Yes! This recipe works well with ground turkey or lamb if you want to try something different.
How long does it take to cook Mac and Cheese Meatloaf Casserole?
The total time from prep to finish is about 1 hour and 8 minutes, including both preparation and baking time.
Final Thoughts
Mac and Cheese Meatloaf Casserole is a deliciously hearty meal that combines two favorites into one comforting dish. It’s versatile enough to allow for various ingredient substitutions based on what you have at home. Whether you’re feeding a family or looking for leftovers, this recipe is sure to please!
Did You Enjoy Making This Recipe? Please rate this recipe with ⭐⭐⭐⭐⭐ or leave a comment.
📖 Recipe Card
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Mac and Cheese Meatloaf Casserole
- Total Time: 1 hour 10 minutes
- Yield: Approximately 6 servings 1x
Description
Mac and Cheese Meatloaf Casserole is the ultimate comfort food that combines two favorites into one delicious dish. This hearty casserole features a savory ground beef meatloaf base topped with creamy macaroni and cheese, creating a satisfying meal perfect for family dinners or casual gatherings. With its unique blend of flavors and textures, this dish will impress everyone at your table. Whether you’re enjoying it on a weeknight or serving it at a special occasion, this Mac and Cheese Meatloaf Casserole is sure to become a beloved staple in your home.
Ingredients
- 2 lbs lean ground beef
- 30 Ritz Crackers
- 1 cup ketchup
- 1 cup barbecue sauce
- 3 cups macaroni noodles
- 2 cups milk
- 10.5 oz condensed cheddar cheese soup
- 4 cups shredded mozzarella and cheddar cheese blend
- 1 teaspoon salt
- 1 teaspoon pepper
- 1 tablespoon garlic powder
- 1 tablespoon onion powder
Instructions
- Preheat the oven to 350°F (175°C).
- In a medium bowl, mix ketchup and barbecue sauce; set aside.
- In a large bowl, combine ground beef, crushed Ritz Crackers, onion soup mix, eggs, and half of the ketchup-barbecue mixture; mix well.
- Transfer the meatloaf mixture into a greased 9 x 13-inch baking dish; spread evenly and top with remaining sauce mixture. Bake for 30 minutes.
- Cook macaroni noodles as per package instructions; drain.
- In a large bowl, whisk together milk and cheddar cheese soup until smooth. Stir in spices and cooked macaroni; then add shredded cheese.
- Pour the mac and cheese mixture over the baked meatloaf and sprinkle with remaining cheese. Bake for an additional 17-20 minutes until golden.
- Prep Time: 20 minutes
- Cook Time: 50 minutes
- Category: Main
- Method: Baking
- Cuisine: Comfort Food
Nutrition
- Serving Size: 1 generous portion (about 280g)
- Calories: 570
- Sugar: 8g
- Sodium: 885mg
- Fat: 27g
- Saturated Fat: 12g
- Unsaturated Fat: 15g
- Trans Fat: 0g
- Carbohydrates: 53g
- Fiber: 2g
- Protein: 34g
- Cholesterol: 135mg





